We present 12 yr of monitoring of the gravitational lens Q0142-100 from the Teide Observatory. The data, taken from 1999 to 2010, comprise 105 observing nights with the IAC80 Telescope. The application of the δ2 method to the dataset leads to a value for the time delay between both components of the system of 72 ± 22 days (68% confidence level), consistent within uncertainties with the most recent results. With this value in mind a possible microlensing event is detected in Q0142-100.