We report on the cometary activity of the minor body P/2010 C1 (Scotti), an active Centaur observed at 5.51 AU. The long-term dynamical behavior of this target is characterized by a close encounter with Saturn, which in 1877 drastically decreased its perihelion distance and semi-major axis to present values. It is probably a "transition" active object, moving towards the inner part of the Solar System, on its way to become a "classical" Jupiter Family comet. P/2010 C1 (Scotti) has a reddish coma (V - R = 0.498 ± 0.049, R - I = 0.665 ± 0.061), characterized by an intermediate cometary activity (R-Af 39 ± 1 cm). Its present quite distant perihelion distance (q = 5.24 AU) makes it interesting for the more general debate on comet-like activity in the region beyond 5 AU, where there is no more significant H2O sublimation to sustain a classical water-driven coma.