In the last years thoughtful quantitative analyses of extragalactic blue massive stars have shown not only that these studies are doable even at large distances (e.g. ˜2 Mpc away), but also essential for a better understanding of host galaxies and stellar evolution, in environments with different metallicities. Carrying out a systematic analysis is mandatory. We present in this work the tools and the FASTWIND stellar grids designed for overcoming this issue, measuring stellar parameters and chemical abundances. We have applied these techniques to the complete sample of blue massive stars observed in NGC 3109, a low metallicity irregular galaxy at 1.3 Mpc, by the ARAUCARIA project and presented by Evans et al. (2007). We report the first systematic quantitative analysis in this galaxy, together with the stellar parameters and the evolution stages of these objects. The chemical composition obtained will shed new light about the chemical composition and distribution along NGC 3109.