The dynamics of isolated galaxy pairs represents an important tool to investigate the behaviour of gravity in the low acceleration regime. Statistical analysis of a large sample of galaxy pairs led to the noticeable discovery of a region of preferred 3-dimensional velocities centered at ~150 and ~100 km s-1 wide, a feature hard to justify in the context of numerical simulations of cosmological structure formation. It is shown here that such a feature is expected within the framework of the modified Newtonian dynamics, which, however, predicts it to be centered at ~ 170 Km s-1.