The Mn I 543.25 nm spectral line has unusually broad line profile due to its hyperfine structure. Here we present the results of LTE calculation of the synthetical profile of the Mn I 543.25 nm line in the solar spectrum. We used the Oxford total absorption oscillator strength measurements as the first approximation for hyperfine structure. The observed spectrum was taken from the High Resolution Solar Spectrum Atlas. The relative intensities of six hyperfine components were varied to obtain a good fit with the observed line profile.