A general study of the fermionic structure of the 331 models with eta arbitrary shows the possibility of obtaining 331 vector-like models with mirror fermions. On one hand, the existence of mirror fermions gives a possible way to fit the discrepancy in the bottom quark asymmetries from the prediction of the standard model. On the other hand, the vector-like nature of the model permits to address the problem of the fermion mass hierarchy, and in particular the problem of the neutrino mass and mixing pattern. Specifically, we consider a model with four families and eta =-1/sqrt{3} where the additional family corresponds to a mirror fermion of the third generation of the Standard Model. We also show how to generate ansatzs about the mass matrices of the fermions according to the phenomenology. In particular, it is possible to get a natural fit for the neutrino hierarchical masses and mixing angles. Moreover, by means of the mixing between the third quark family and its mirror fermion, a possible solution for the A_{FB}^{b} discrepancy is obtained.